A study of empyema thoracis and role of intrapleural streptokinase in its management

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A study of empyema thoracis and role of intrapleural streptokinase in its management

BACKGROUND Clinical spectrum, microbiology and outcome of empyema thoracis are changing. Intrapleural instillation of fibrinolytic agents is being increasingly used for management of empyema thoracis. The present study was carried out to describe the clinical profile and outcome of patients with empyema thoracis including those with chronic empyema and to study the efficacy and safety of intrap...

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Intrapleural fibrinolytics in management of empyema thoracis.

STUDY OBJECTIVE To determine the success and complication rates of fibrinolytic therapy (FL) in the treatment of thoracic empyema. DESIGN AND PATIENTS Between December 1992 and November 1994, all patients referred with empyema thoracis (ET) were offered FL. FL consisted of streptokinase (275,000 +/- 170,000 IU) or urokinase (121,000 +/- 57,000 IU) daily for a mean of 6.2 +/- 2.1 days. SETTI...

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Intrapleural streptokinase in the management of empyema.

BACKGROUND Significant morbidity and mortality result from the ineffective evacuation of empyema. Failure of conventional first line treatment with closed intercostal tube drainage and antibiotic therapy may result in fibrin deposition and loculated empyema. Enzymatic debridement using intrapleural instillation of streptokinase is a non-invasive therapeutic option which may obviate the need for...

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Non surgical treatment of empyema thoracis with intrapleural streptokinase in a patient with AIDS.

After unsuccessful treatment with intercostal tube drainage and antibiotics intrapleural streptokinase was used to treat successfully an empyema in a man with AIDS and advanced cutaneous Kaposi's sarcoma who was unfit for surgical decortication. The role of this technique in the management of HIV positive patients with empyema is discussed.

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Intrapleural Streptokinase in the Management of Pleural Empyema

thoracic surgery with poor prognosis unless treated properly. It can cause sepsis and other complications which may increase morbidity and mortality. The treatment of choices in pleural empyema are thoracentesis, intercostal tube or pleural catheter drainage, video-assisted thoracic surgery (VATS) and open surgery (1, 2). Tube drainage often fails if the empyema is loculated with fibrinous adhe...

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ژورنال

عنوان ژورنال: BMC Infectious Diseases

سال: 2004

ISSN: 1471-2334

DOI: 10.1186/1471-2334-4-19